Cosmetic ingredient peptide Glutathione CAS NO.70-18-8

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Glutathione

1.Basic information:

INCI Name: Glutathione

Cas No: 70-18-8

Formula: C10H17N3O6S

Molecular: 307.32

Sequence: Glu-Cys-Gly

Purity: >95%

Boiling Point: 756.4±60.0 °C at 760 mmHg

Vapour Pressure:: 0.0±5.5 mmHg at 25°C

Enthalpy of Vaporization: 119.9±6.0 kJ/mol

Flash Point: 411.3±32.9 °C

Source: synthetic

Stability: stable

Appearance: white powder

Formulation: available for your reference

Delivery: promptly from stock

2.Functions: antioxidant, whitening

3.Description:

Glutathione (GSH) is an important antioxidant in plants, animals, fungi, and some bacteria and archaea, preventing damage to importantcellular components caused by reactive oxygen species such as free radicals, peroxides, lipid peroxides and heavy metals. It is atripeptide with a gamma peptide linkage between the carboxyl group of the glutamate side-chain and the amine group of cysteine (which is attached by normal peptide linkage to a glycine).

Thiol groups are reducing agents, existing at a concentration around 5 mM in animal cells. Glutathione reduces disulfide bonds formed within cytoplasmic proteins to cysteines by serving as an electron donor. In the process, glutathione is converted to its oxidized form,glutathione disulfide (GSSG), also called L-(–)-glutathione.

Once oxidized, glutathione can be reduced back by glutathione reductase, using NADPH as an electron donor. The ratio of reduced glutathione to oxidized glutathione within cells is often used as a measure of cellular toxicity. 

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